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Creatinine Clearance (Cockcroft-Gault)

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Estimate creatinine clearance (eGFR proxy) for drug dosing in renal impairment.

Aroha Tane RNVerified

BN (Hons), Registered Nurse, NZNO Member

Registered nurse with 10 years in emergency and critical care across NZ. Specialises in clinical decision support and drug calculation safety.

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About the Creatinine Clearance (Cockcroft-Gault)

The Cockcroft-Gault equation estimates creatinine clearance (CrCl) as a surrogate for GFR. It is widely used for drug dose adjustments in renal impairment.

How it works

CrCl = \frac{(140 - \text{age}) \times \text{weight} \times F}{\text{creatinine (\mu mol/L)}}

Tips to improve your result

  • 1.

    F = 1.23 for males, 1.04 for females. Results in mL/min.

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